Go to the Kitiyim (Cyprus) and Kedar (presumably the Arabian Peninsula) and see whether any nation ever traded in their "gods" - even though those "gods" are no gods at all! But Israel exchanged the real G-d for non-gods! This is two sins: first, turning away from G-d, who is like a spring of living water; second, turning to idols, who are liked cracked wells that can't even hold water.
Is Israel a slave to be bought and sold between different owners? (No.) Why are they now prey? Young lions, referring to the kings of the various nations, fight over them, conquering their lands. The Jews turned to the Egyptians for help, but the Egyptians will also trouble them. That's what you get for forsaking G-d. You want to drink from the Nile, where they drowned your children? You'll end drinking from the Euphrates when you're exiled to Assyria!
The people's own sins will bring evil upon them. They will learn the hard way what it is to turn one's back on G-d. G-d removed the Jews from Egyptian slavery and they promised to keep the Torah, but on every hilltop they're worshipping idols! (Verse 20 is a kri/k'siv, in which the word is spelled and pronounced two different ways. The text is read "lo e'evor," I will not sin, but it is written "lo e'evod" - I will not serve, referring to idols.)
G-d says, referring to the Jews, that He planted good vines, but they grew wild. (The word "shoreik" in verse 21, referring to the good vine, has a numerical value of 606. All mankind has an obligation to keep the seven universal laws; when the Jews received the Torah, they received an additional 606 commandments.)
Even if the people would scrub themselves with soap, they would be stained by their sins. How can they deny it? They're like a young camel that loves to wander, or a wild donkey that's used to the wilderness; who can tame them? If someone tries, they will not succeed. Only when they have become full of their sins will they be able to be overcome.
Stop wandering like those wild animals or you'll end up barefoot and thirsty in exile! People gave up on G-d because they saw sinners prospering and decided to follow them. They are embarrassed, like a thief is ashamed when he gets found out. They considered idols of wood and stone to be their gods, and when things go bad, they ask the real G-d to save them! Where have the idols gone? Let them do it!
Why don't they turn back to G-d and call Him "Father" again?
Excerpted from The OU's Nach Yomi